GLP-1 Cost & Weight Loss Calculator
See exactly how much Wegovy, Zepbound, Foundayo (orforglipron), Ozempic, Mounjaro, and oral Wegovy will cost - and how much weight you can expect to lose - over 3, 6, 12, 18, or 24 months.
Your inputs
FDA-approved for chronic weight management. Most commonly prescribed for weight loss.
Phase 3 subgroup data: women lose ~2–4% more body weight than men. Skip to use the population average.
Your projection
Weight loss over time
Pounds lost based on trial data
Cumulative cost
What you'll have spent by each month
How 12-month projections compare across all GLP-1s
| Drug | Monthly | Total cost | Weight loss | $/lb lost | |
|---|---|---|---|---|---|
| Foundayo (orforglipron) | $149 | $1,788 | 27 lbs (12.3%) | $66 | Get → |
| Wegovy (oral 25mg) | $149 | $1,788 | 25.5 lbs (11.6%) | $70 | Get → |
| Zepbound | $299 | $3,588 | 41.4 lbs (18.8%) | $87 | Get → |
| Wegovy | $349 | $4,188 | 28 lbs (12.7%) | $150 | Get → |
| CagriSema | $599 | $7,188 | 38.3 lbs (17.4%) | $188 | Get → |
Sorted by cost-efficiency (lowest $/lb lost first). Some drugs may not be available on the selected payment channel.
Live price comparison - every channel, every drug
Manufacturer direct prices (LillyDirect, NovoCare) are usually cheapest. Updated May 2026.
| Drug | Insurance | Mfr direct | Telehealth (brand) | Telehealth (compd) | Cash retail | Get it |
|---|---|---|---|---|---|---|
| Wegovy 14.9% weight loss | $63 | $349 | $329 | $249 cheapest | $1,349 | Get → |
| Ozempic 11.6% weight loss | $63 | - | $399 | $199 cheapest | $998 | Get → |
| Wegovy (oral 25mg) 13.6% weight loss | $63 | $149 cheapest | $449 | - | $1,349 | Get → |
| Zepbound 22.5% weight loss | $88 | $299 cheapest | $499 | $299 cheapest | $1,059 | Get → |
| Mounjaro 20.9% weight loss | $88 | - | $499 | $299 cheapest | $1,069 | Get → |
| Saxenda 8.4% weight loss | $63 | - | $399 cheapest | - | $1,349 | Get → |
| Foundayo (orforglipron) 14.7% weight loss | $63 | $149 cheapest | - | - | $1,099 | Get → |
More tools
Free calculators built for GLP-1 users. No login, no ads in the way.
Stay ahead of every GLP-1 development
We'll email you when something actually matters: new FDA approvals (Foundayo, CagriSema, retatrutide), pricing drops at LillyDirect/NovoCare, telehealth deals, clinical trial results, FDA recalls, and insurance policy changes. ~1-2 emails/month. No filler.
Individual drug guides
Deep-dive cost, dosing, and weight-loss timeline for each GLP-1 medication.
Head-to-head comparisons
See exactly how each pair of GLP-1s stacks up on cost, weight loss, and side effects.
Cost & access guides
Real-world paths to afford a GLP-1 - denials, savings cards, cash-pay, and appeals.
Does your insurance cover GLP-1s?
Coverage varies dramatically by carrier. Check yours below.
GLP-1 cost by state
Cost and access vary by state Medicaid policies, employer plans, and pharmacy networks.
Track Foundayo (orforglipron) pricing and availability
Eli Lilly's daily oral pill Foundayo (orforglipron) was FDA-approved April 1, 2026 and starts at $149/mo via LillyDirect. We'll email you when pricing tiers change, insurance coverage expands, or new head-to-head data lands vs. Wegovy and Zepbound.
Frequently asked questions
Where does the weight-loss data come from?
Each drug's expected weight loss is modeled from its FDA phase 3 trial primary endpoint. Wegovy uses STEP-1 (14.9% at 68 weeks), Zepbound uses SURMOUNT-1 (22.5% at 72 weeks), Mounjaro uses SURPASS, oral Wegovy uses OASIS-4, and Foundayo (orforglipron) uses ATTAIN-1. We model the curve as an exponential approach to plateau, which closely matches published trial data.
Where do the prices come from?
Manufacturer wholesale (WAC) prices come from Novo Nordisk and Eli Lilly public pricing. Self-pay manufacturer prices come from LillyDirect and NovoCare. Telehealth prices come from public pricing pages at Hims, Ro, Found, Lemonaid, and LifeMD as of May 2026. Insurance copays are typical ranges; your actual copay depends on your specific plan.
Why is the cost-per-pound number useful?
It lets you compare drugs apples-to-apples on cost-efficiency. A drug that costs more per month but produces dramatically more weight loss may actually be cheaper per pound lost. Use the comparison table to find your best option.
What about side effects, contraindications, and dose escalation?
This calculator focuses on cost and efficacy. It does not model side effects, drug interactions, dose escalation schedules, or individual response variation. These are critical factors and require a licensed prescriber. We strongly recommend consulting a doctor or telehealth NP/RD before starting any GLP-1.
Are compounded GLP-1s still legal?
FDA cracked down on compounded semaglutide in 2025 after Novo Nordisk’s shortage was resolved. Compounded tirzepatide remains in a gray area. Telehealth platforms like Hims and Ro have shifted toward branded drugs and lower-dose self-pay vials. The "telehealth-compounded" option in this calculator may not be available for all drugs.
Which GLP-1 has the highest weight loss?
Among FDA-approved drugs, Zepbound (tirzepatide) has the highest in clinical trials at 22.5% mean weight loss in SURMOUNT-1. Mounjaro (same molecule) shows similar off-label results. Pending drugs like CagriSema (20.4%) and retatrutide (28.7% in phase 3) may exceed this once approved.
Is GLP-1 covered by insurance?
It varies. Drugs FDA-approved for type 2 diabetes (Ozempic, Mounjaro) are widely covered for diabetic patients. Drugs FDA-approved for weight loss (Wegovy, Zepbound, Saxenda) face more denials-many plans require BMI ≥30 plus a comorbidity, and some exclude weight-loss drugs entirely. Medicare does not cover drugs prescribed solely for weight loss.