Wegovy (oral 25mg) (semaglutide (tablet))
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New oral formulation, FDA-approved January 2026. Daily pill instead of weekly injection. Manufactured by Novo Nordisk. FDA-approved status: weight-loss.
Peak weight loss
13.6%
Trial
OASIS-4
Time to peak
68 wks
List price
$1,349/mo
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Wegovy (oral 25mg) pricing across every channel
Manufacturer direct prices (LillyDirect, NovoCare) are usually cheapest. Updated May 2026.
| Drug | Insurance | Mfr direct | Telehealth (brand) | Telehealth (compd) | Cash retail | Get it |
|---|---|---|---|---|---|---|
| Wegovy (oral 25mg) 13.6% weight loss | $63 | $149 cheapest | $449 | - | $1,349 | Get → |
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Wegovy (oral 25mg) cost in 2026
| Payment channel | Monthly | 12 months |
|---|---|---|
| Covered by insurance ($25–150 copay) | $63 | $756 |
| Manufacturer self-pay (LillyDirect / NovoCare) | $149 | $1,788 |
| Telehealth: brand name (Hims, Ro, Found) | $449 | $5,388 |
| Telehealth: compounded (limited post-FDA crackdown) | Not available | - |
| Cash retail (full list price) | $1,349 | $16,188 |
Dosing
Daily oral tablet. Take on empty stomach with small sip of water; wait 30 min before food.
What to expect on Wegovy (oral 25mg)
For someone starting at 220 lbs on Wegovy (oral 25mg) for 12 months, the projection is:
Expected loss at 12 mo
25.5 lbs
Final weight
194.5 lbs
Cost / lb lost
$211
Modeled from OASIS-4 phase 3 data. Adjust for your own weight on the full calculator.
✓ Pros
- No injections - daily oral pill
- Same molecule as Wegovy injection
- 13.6% average weight loss in OASIS-4
- Easier to skip a dose without long-acting tail
✗ Cons
- Strict fasting requirements before/after dose
- Slightly lower weight loss than injection (13.6% vs 14.9%)
- Daily dosing may hurt adherence vs weekly injection
- Newer drug - fewer real-world data points
Common side effects
Most-reported in OASIS-4. Side effects are typically worst during dose escalation and improve over time.
NauseaDiarrheaConstipationVomiting
→ Full Wegovy (oral 25mg) side effects guide (timing, severity, when to call)Related cost guides
- → GLP-1 Savings Cards Compared - manufacturer copay programs for Wegovy (oral 25mg) and others
- → GLP-1 Prior Authorization Guide - what insurers want for Wegovy (oral 25mg) and how to win an appeal
- → Cheapest GLP-1 Finder - all 8 drugs ranked by cost-per-pound-lost
Compare Wegovy (oral 25mg) to other GLP-1s
Wegovy (oral 25mg) coverage by major insurer
Coverage stance and per-carrier details for Wegovy (oral 25mg). Each link goes to the full prior-auth requirements, cost table, and appeal playbook for that carrier.
Aetna → Wegovy (oral 25mg)Plan-dependentAnthem BCBS → Wegovy (oral 25mg)Plan-dependentCigna → Wegovy (oral 25mg)Plan-dependentUnitedHealthcare → Wegovy (oral 25mg)Plan-dependentKaiser → Wegovy (oral 25mg)Plan-dependentHumana → Wegovy (oral 25mg)RarelyMedicare → Wegovy (oral 25mg)RarelyMedicaid → Wegovy (oral 25mg)Rarely
Related guides
How much does oral Wegovy 25mg cost? →
NovoCare $149/mo for low doses - cheapest branded GLP-1 cash-pay path in 2026.
How much does Foundayo (orforglipron) cost? →
LillyDirect $149/mo lowest dose - first daily oral GLP-1 with no food restrictions, FDA-approved April 2026.
Wegovy without insurance →
Cheapest legal cash-pay paths if your plan denies you.
Wegovy savings card →
How the $25 copay path actually works, plus what to do if you do not qualify.
Cheapest GLP-1 in 2026 →
Side-by-side cash-pay prices for every FDA-approved GLP-1, ranked by $/lb lost.
GLP-1 savings cards compared →
Wegovy, Zepbound, Mounjaro, Ozempic - eligibility and the government-insurance trap.
Medical disclaimer: This calculator provides estimates only based on phase 3 clinical trial data and publicly listed prices. It is not medical advice. Real-world weight loss varies significantly. Consult a licensed healthcare provider before starting any medication.