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GLP1Cost

Wegovy (semaglutide (injection))

By Anthony K C Fong, Esq.·Last reviewed:
NY State Bar #5361159 · Hawaii State Bar · Founder, GLP1Cost.org

FDA-approved for chronic weight management. Most commonly prescribed for weight loss. Manufactured by Novo Nordisk. FDA-approved status: weight-loss.

Peak weight loss
14.9%
Trial
STEP-1
Time to peak
68 wks
List price
$1,349/mo
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Wegovy pricing across every channel

Manufacturer direct prices (LillyDirect, NovoCare) are usually cheapest. Updated May 2026.

DrugInsuranceMfr directTelehealth (brand)Telehealth (compd)Cash retailGet it
Wegovy
14.9% weight loss
$63$349$329$249
cheapest
$1,349Get →
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Wegovy cost in 2026

Payment channelMonthly12 months
Covered by insurance ($25–150 copay)$63$756
Manufacturer self-pay (LillyDirect / NovoCare)$349$4,188
Telehealth: brand name (Hims, Ro, Found)$329$3,948
Telehealth: compounded (limited post-FDA crackdown)$249$2,988
Cash retail (full list price)$1,349$16,188

Dosing

Weekly subcutaneous injection. Dose escalates from 0.25 mg → 0.5 → 1.0 → 1.7 → 2.4 mg over 16+ weeks.

What to expect on Wegovy

For someone starting at 220 lbs on Wegovy for 12 months, the projection is:

Expected loss at 12 mo
28 lbs
Final weight
192 lbs
Cost / lb lost
$141

Modeled from STEP-1 phase 3 data. Adjust for your own weight on the full calculator.

✓ Pros

  • FDA-approved specifically for weight loss
  • Robust 14.9% average weight loss in STEP-1
  • Wide telehealth and pharmacy availability
  • Once-weekly injection (good adherence)

✗ Cons

  • High list price ($1,349/mo without coverage)
  • Insurance often denies for weight loss without comorbidity
  • Mild-to-moderate GI side effects common during titration
  • Lower efficacy than tirzepatide-based alternatives

Common side effects

Most-reported in STEP-1. Side effects are typically worst during dose escalation and improve over time.

NauseaDiarrheaConstipationVomitingHeadache
→ Full Wegovy side effects guide (timing, severity, when to call)

Related cost guides

Compare Wegovy to other GLP-1s

Run a personalized Wegovy projection →

Wegovy coverage by major insurer

Coverage stance and per-carrier details for Wegovy. Each link goes to the full prior-auth requirements, cost table, and appeal playbook for that carrier.

Related guides

Medical disclaimer: This calculator provides estimates only based on phase 3 clinical trial data and publicly listed prices. It is not medical advice. Real-world weight loss varies significantly. Consult a licensed healthcare provider before starting any medication.
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