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GLP1Cost

Mounjaro (tirzepatide (injection))

By Anthony K C Fong, Esq.·Last reviewed:
NY State Bar #5361159 · Hawaii State Bar · Founder, GLP1Cost.org

Same active ingredient as Zepbound but indicated for diabetes. Off-label weight loss common. Manufactured by Eli Lilly. FDA-approved status: type-2-diabetes.

Peak weight loss
20.9%
Trial
SURPASS-2 / off-label
Time to peak
72 wks
List price
$1,069/mo
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Mounjaro pricing across every channel

Manufacturer direct prices (LillyDirect, NovoCare) are usually cheapest. Updated May 2026.

DrugInsuranceMfr directTelehealth (brand)Telehealth (compd)Cash retailGet it
Mounjaro
20.9% weight loss
$88-$499$299
cheapest
$1,069Get →
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Mounjaro cost in 2026

Payment channelMonthly12 months
Covered by insurance ($25–150 copay)$88$1,056
Manufacturer self-pay (LillyDirect / NovoCare)Not available-
Telehealth: brand name (Hims, Ro, Found)$499$5,988
Telehealth: compounded (limited post-FDA crackdown)$299$3,588
Cash retail (full list price)$1,069$12,828

Dosing

Weekly subcutaneous injection, same titration as Zepbound (2.5 → 15 mg).

What to expect on Mounjaro

For someone starting at 220 lbs on Mounjaro for 12 months, the projection is:

Expected loss at 12 mo
38.5 lbs
Final weight
181.5 lbs
Cost / lb lost
$156

Modeled from SURPASS-2 / off-label phase 3 data. Adjust for your own weight on the full calculator.

✓ Pros

  • Identical molecule to Zepbound
  • Easier insurance approval if you have type 2 diabetes
  • Strong cardiovascular and renal data (SURPASS-CVOT, SURMOUNT-MMO)

✗ Cons

  • Off-label for weight loss - most insurers deny
  • Cash-pay typically more expensive than Zepbound LillyDirect option

Common side effects

Most-reported in SURPASS-2 / off-label. Side effects are typically worst during dose escalation and improve over time.

NauseaDiarrheaConstipationVomiting
→ Full Mounjaro side effects guide (timing, severity, when to call)

Related cost guides

Compare Mounjaro to other GLP-1s

Run a personalized Mounjaro projection →

Mounjaro coverage by major insurer

Coverage stance and per-carrier details for Mounjaro. Each link goes to the full prior-auth requirements, cost table, and appeal playbook for that carrier.

Related guides

Medical disclaimer: This calculator provides estimates only based on phase 3 clinical trial data and publicly listed prices. It is not medical advice. Real-world weight loss varies significantly. Consult a licensed healthcare provider before starting any medication.
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