Foundayo (orforglipron) (orforglipron (tablet))
Eli Lilly's oral GLP-1, FDA-approved April 1, 2026 under the National Priority Voucher Program. First non-peptide small-molecule GLP-1 receptor agonist. Distributed via LillyDirect (started Apr 6, 2026) plus retail/telehealth (CVS, Walgreens, Ro) since Apr 9, 2026. Manufactured by Eli Lilly. FDA-approved status: weight-loss.
Foundayo (orforglipron) pricing across every channel
Manufacturer direct prices (LillyDirect, NovoCare) are usually cheapest. Updated May 2026.
| Drug | Insurance | Mfr direct | Telehealth (brand) | Telehealth (compd) | Cash retail | Get it |
|---|---|---|---|---|---|---|
| Foundayo (orforglipron) 14.7% weight loss | $63 | $149 cheapest | - | - | $1,099 | Get → |
Foundayo (orforglipron) cost in 2026
| Payment channel | Monthly | 12 months |
|---|---|---|
| Covered by insurance ($25–150 copay) | $63 | $756 |
| Manufacturer self-pay (LillyDirect / NovoCare) | $149 | $1,788 |
| Telehealth: brand name (Hims, Ro, Found) | Not available | - |
| Telehealth: compounded (limited post-FDA crackdown) | Not available | - |
| Cash retail (full list price) | $1,099 | $13,188 |
Dosing
Once-daily oral tablet. No fasting requirement (small-molecule, not peptide). Can be taken any time of day with or without food.
What to expect on Foundayo (orforglipron)
For someone starting at 220 lbs on Foundayo (orforglipron) for 12 months, the projection is:
Modeled from ATTAIN-1 phase 3 data. Adjust for your own weight on the full calculator.
✓ Pros
- Daily pill with NO food or water restrictions (advantage over oral Wegovy 25 mg)
- Non-peptide small molecule - easier manufacturing and scaling
- 14.7% average weight loss in ATTAIN-1
- LillyDirect self-pay starts at $149/mo for the lowest dose
- Medicare Part D coverage as low as $50/mo beginning July 1, 2026
✗ Cons
- New molecule (April 2026 approval) - limited real-world safety data outside trials
- Daily adherence required
- Higher doses (14.5/17.2 mg) price up to $349/mo out of refill window
Common side effects
Most-reported in ATTAIN-1. Side effects are typically worst during dose escalation and improve over time.
Related cost guides
- → GLP-1 Savings Cards Compared - manufacturer copay programs for Foundayo (orforglipron) and others
- → GLP-1 Prior Authorization Guide - what insurers want for Foundayo (orforglipron) and how to win an appeal
- → Cheapest GLP-1 Finder - all 8 drugs ranked by cost-per-pound-lost
Compare Foundayo (orforglipron) to other GLP-1s
Foundayo (orforglipron) coverage by major insurer
Coverage stance and per-carrier details for Foundayo (orforglipron). Each link goes to the full prior-auth requirements, cost table, and appeal playbook for that carrier.